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GLP-1 and GIP stimulate insulin secretion from these cells in a glucose-dependent manner, meaning that insulin release intensifies in response to heightened plasma glucose levels

Physiol Rev 56(4):778826 Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D et al (2008) DrugBank: a knowledgebase for drugs, drug actions and drug targets

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In addition, as seen in Dpp4 / mice, basal levels of HGP were unchanged, and Dpp4 hep/ mice showed lower HGP under clamp conditions and greater insulin suppression of HGP (Figure 1, I and J)

Gastrointestinal side effects are among the most common with Wegovy and include: Nausea and vomiting Diarrhoea or constipation Abdominal pain and bloating Gastro-oesophageal reflux Lisdexamfetamine can also cause gastrointestinal upset, including nausea, dry mouth, and abdominal pain

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