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In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa

& Enriquez, J

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It is the fastest way to deliver nutrients throughout the body, because it bypasses the digestive system and goes directly into the organs, resulting in a 90-100% absorption rate (as opposed to typically 20-50% absorption rate possibly orally)