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Additional concerns with regard to the safety of hydroquinone is based on studies that suggest that benzene, which is a known leukemogenic agent, is metabolized into hydroquinone as a major by-product (Norlund et al., 2006)

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2 In this study, following 36 weeks of therapy with once weekly SC tirzepatide (10 or 15 mg), participants (n = 670) were randomized to continue tirzepatide or switch to placebo for an additional 52 weeks