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You can also follow this general advice for managing side effects on GLP-1s: Eat smaller portions, more often, and more slowly Only eat when youre hungry, and stop when youre full Sip slowly on clear, cold drinks like water Avoid anything too sweet, spicy, fatty, or fried After eating, go for a gentle stroll in the fresh air The Possibility of a Temporary Weight Stall Tirzepatide is generally considered more effective, so when you switch from tirzepatide to semaglutide, you may experience an increase in your appetite and some rebound weight gain

Campbell Jonathan E, Drucker DJ

Mingrone G, Greco AV, Capristo E, Benedetti G, Giancaterini A, De Gaetano A, et al

fragilis triggered GI inflammation in colonic epithelial cells via G-protein coupled receptor-35 (GPCR35) binding

Rather than competing with each other, they complement each other

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