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The 2 mg starting step is not expected to deliver a maintenance-level effect its only job is to introduce the molecule gently

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Previous studies have reported that increased oxidative stress in the brain of diabetic rats can lead to cognitive and behavioral defects (Ling et al., 2018), and increased ROS in the brain caused the dysfunction of antioxidant enzymes and weakened cognitive ability (Kumar and Menon, 1993)

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This protocol uses 360-degree surround cooling technology to ensure an even temperature distribution across the targeted tissue