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The investigators in this study are in no way promoting binge drinking, however, it must be recognized that some individuals are more prone to hangovers than others, even when consuming smaller amounts of alcohol and alcohol intoxication and hangover symptoms are significant issues in society today

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Certainty of evidence Paired reviewers with experience in using GRADE assessed the certainty of evidence independently and resolved discrepancies by discussion

Some medical professionals question its legitimacy , primarily because of the lack of peer-reviewed studies that support its efficacy

"-Carnitine supplementation for adults with end-stage kidney disease requiring maintenance hemodialysis: a systematic review and meta-analysis"