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Rodent thyroid C-cells express high levels of GLP-1 receptors

Pharmaceutics 15:117

The UK Chief Medical Officers recommend adults engage in: At least 150 minutes of moderate-intensity activity weekly Weight-bearing exercises such as walking, jogging, dancing, or tennis Resistance training at least twice weekly to maintain muscle mass and bone strength Balance exercises to reduce fall risk, particularly important for older adults Patients experiencing significant weight loss should aim for a gradual, sustainable rate of 0.51kg per week where possible

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Watch the full conversation on YouTube Listen now When I pushed Layne on what actually works long-term, he gave me a concrete list: they pick a sustainable plan they can still follow when life gets hard, they self-monitor by weighing in regularly as a feedback loop, they eat meals instead of snacking, they use some form of deliberate restraint like tracking macros or an eating window, and they exercise not to burn calories, but to stay sensitive to satiety signals