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Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations

Serious adverse outcomes are categorized according to FDA-defined criteria, including: mortality (DE), life-threatening conditions (LT), hospitalization (HO), disability (DS), congenital anomalies (CA), and other medically significant events (OT)

Rather than applying standardized dosing schedules universally, the program emphasizes individualized titration aligned with tolerance and metabolic response

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This is especially true if you have any health issues