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Online monitoring of metabolite dynamics in continuous fermentor cultures A Biostat A fermentor (Sartorius Stedim Systems GmbH, Guxhagen, Germany) was used to measure population-synchronised metabolic oscillations in continuous cultures with respect to the yeast metabolic cycle 34

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Nevertheless, the mean age at death for individuals born between 1985 and 1999 has been 29 years, and earlier diagnosis by newborn screening, treatment with more palatable cystine-depleting agents, and trials with gene therapy are critical current pursuits