In the MVP cohort 20 , rs10305420 is associated significantly with BMI-associated traits ( P value around 2 10 15 ), although it is in linkage with an upstream association (Extended Data Fig
Paajanen, H., Erkintalo, M., Kuusela, T., Dahlstrom, S
These results are often better than what people see with diet and exercise alone or some other medications
In sensitivity analysis, we also included an isoform of l-carnitine, acetyl-carnitine, proxied by three genetic variants reaching genome-wide significance from the same GWAS as l-carnitine [20]
The class has been shown to have a direct myocardial effect, decrease postprandial lipemia and reduce BP
Bohannon DG, Long D, Kim WK