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(Academic Press, 1996)

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Lack of sleep also makes you hungrier, causes you to store more fat, and makes your body less sensitive to the hormone insulin, sabotaging attempts to lose weight and increasing your risk of developing type 2 diabetes or cardiovascular disease

Enrolling 17,604 adults aged 45 or older with established cardiovascular disease and a BMI of 27 or higher (without diabetes), SELECT showed that semaglutide 2.4 mg reduced the composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke by 20% over a mean follow-up of nearly 40 months

Oxidative damage to the heart often leads to heart disease like stroke, heart attacks, and other life-threatening conditions