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However, despite improvements in OSA-related symptoms and hypertension, PAP has not demonstrated a benefit on composite cardiovascular endpoints in randomized controlled trials for primary [23] or secondary cardiovascular prevention [24,25,26]

Kaberi Dasgupta, a professor of medicine at McGill University and a researcher, says this would be good news for people who have excess weight and resulting complications but who can't currently afford the branded medications

These defects are inborn errors of metabolism that affect all stages of homocysteine metabolism.2 Dietary folate, vitamin B6, and vitamin B12 play a significant role in regulating plasma levels of homocysteine

That is a meaningful investment, especially for a product whose benefits are modest compared to pharmaceutical alternatives

Veal, E.A., Day, A.M