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While B12 plays a role in cellular energy metabolism, supplementing B12 in a patient who is not deficient does not increase metabolic rate or cause fat loss
The primary aim was to determine AOD9604s impact on body weight, adipose tissue mass, gene expression of 3-AR, and metabolic activity, as well as to evaluate whether the 3-AR is required for its effects [2]
Athletes and competition AOD-9604 is on the World Anti-Doping Agency Prohibited List under category S2.2 (peptide hormones, growth factors, related substances, and mimetics)
For those struggling with weight loss, it could be worth consulting a doctor to see if B12 injections would help
Because of these challenges, many experts agree that the arm is a site best left to a trained provider who can administer the injection safely and correctly
This efficacy limitation, rather than safety concerns, halted further development
