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Russian studies spanning decades suggest Epithalon can restore age-related decline in various organ systems

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However, dehydration can occur indirectly as a secondary consequence of common gastrointestinal side effects, such as nausea, vomiting, or diarrhea, alongside a significantly reduced drive to drink fluids due to profound appetite suppression

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In contrast, novel additive including phosphate-adenine-glucose-guanosine-gluconate-mannitol (PAG3M), Erythro-Sol 5 (E-Sol5), and SOLX (AS-7) have pursued different strategies to allow RBC storage under alkaline conditions 32,33