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NICE guidance (NG28) on type 2 diabetes management does not include the combination of GLP-1 receptor agonists and DPP-4 inhibitors in its recommended treatment algorithms

These drugs have been affecting libido, as Dr Naveed Asif, a GP from London General Practice, explained: From a physical perspective, GLP-1 medications affect smooth muscle activity, which can influence arousability and orgasm due to changes in blood flow to the genital area

Katie, a 46-year-old teacher who lives in the Washington, D.C., suburbs, encountered it after she started taking Eli Lillys Zepbound in March 2024, after years of unsuccessful attempts to lose weight following a medically necessary total hysterectomy

Antioxidants also play a role in energy production

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By engaging both of these pathways, tirzepatide can: Enhance insulin secretion Reduce appetite Slow gastric emptying Improve glycemic (blood sugar) control Clinical research has demonstrated that tirzepatide can result in greater weight loss and improved metabolic health compared to traditional GLP-1 agonists