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The primary evidence regarding tirzepatide's cancer risk comes from the SURPASS clinical trial program for type 2 diabetes and the SURMOUNT trials for weight management

it provides healthy weight loss at a rate of one to two pounds per week

A knowledgeable provider will be honest about the limitations of the evidence rather than repeating marketing claims

Long-term watch items beyond the common GI events that fade within weeks include gallbladder disease (cholelithiasis 1.1% in trials), acute kidney injury (0.5%), and rare cases of pancreatitis (under 1%)

Zepbound has FDA-reviewed labeling and manufacturing

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