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Their effects are marked by increased satiety, reduced appetite, and improved metabolic biomarkers, with a safety profile dominated by mild to moderate gastrointestinal adverse events

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Because GIP receptor activation affects fat metabolism through pathways separate from appetite control, there is a theoretical basis for better weight maintenance at lower tirzepatide doses compared to equivalent semaglutide doses

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Ischemic Optic Neuropathy with Semaglutide: Global Observational Analysis of Sex- and Formulation-Specific Risk. The British Journal of Ophthalmology , Mar