While the kinetics vary widely between products (see table above), in general, the onset of side effects may be delayed 12-48 hours after injection
Efpeglenatide is a long-acting GLP-1RA, which was developed for the management of hyperglycemia in patients with T2D [50]
However, constipation becomes more concerning when it occurs with severe swelling, vomiting, intense pain, or inability to pass gas
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