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A response usually is seen within 48 to 72 hours, with brisk production of new red blood cells

Wnt5a activats Wnt/PCP pathway, upregulating Ras-related C3 botulinum toxin substrate 1(Rac), which can activate JNK, thus aggravating IR in adipose tissue

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In addition, tissue concentrations of malondialdehyde (MDA), a marker of oxidative stress, were elevated in the kidneys of SLC25A45 KO mice relative to control mice

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