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Description

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GIPR:GCGR co-agonism restores normal weight in obese rodents

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Liquid Chromatography-Mass Spectrometry (LC-MS): This confirms the exact molecular mass and identity of the peptide, ensuring no structural variations exist

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NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores

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