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1 Diabetes and Endocrine, Liverpool Hospital, Liverpool, Australia, 2 Diabetes and Endocrine, Western Sydney University, Campbelltown, Australia

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Studies indicate that GLP-1R (glucagon-like peptide-1 receptor), GIPR (glucose-dependent insulinotropic polypeptide receptor), and GCGR (glucagon receptor) act as crucial "regulators" in maintaining human blood glucose balance and are important therapeutic targets for type 2 diabetes and obesity

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Wu YS, Zhu B, Luo AL, Yang L, Yang C (2018) The role of cardiokines in heart diseases: beneficial or detrimental