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Plant Sci 227:133144 Kumar B, Singla-Pareek SL, Sopory SK (2010) Glutathione homeostasis: crucial for abiotic stress tolerance in plants

Introduction The glucagon-like peptide-1 receptor (GLP-1R), expressed in pancreatic beta cells amongst other tissues including brain, lung, stomach, and heart, is activated by the incretin peptide hormone GLP-1, secreted from enteroendocrine L-cells after food intake (1), to regulate postprandial glucose levels via the potentiation of glucose-dependent insulin secretion (24)

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Mechanistically, lactate contributes to the intracellular acetyl-CoA pool through its conversion to pyruvate, followed by subsequent metabolism (74)

DIPEA (7.75 mL, 44.7 mmol) was slowly added to the mixture