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In contrast, inducing autophagy with rapamycin (100 nM) attenuated SIPS

Activation of GSDMD contributes to acute kidney injury induced by cisplatin

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Its thought to work by making more of the milk-producing hormone prolactin

In addition to this, the reactive doxorubicin semiquinone radical can be recycled back to doxorubicin, generating an O 2 - superoxide that leads to reactive H 2 O 2 formation, which is neutralised into H 2 O by the conversion of reduced glutathione (GSH) into its oxidised form (GSSG)

Kaster MP, Machado NJ, Silva HB, Nunes A, Ardais AP, Santana M et al (2015) Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress