Trial data from the STEP program shows an average of 14.9% body weight reduction over 68 weeks
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However, these tumours do not exhibit the characteristic biphasic pattern of melanin-producing, keratin-positive epithelial cells, nor do they show the synaptophysin-positive neuroblast-like cells, which are key features of melanotic neuroectodermal tumour of infancy (Thompson et al., 2025)
Drug type Dual GIP/GLP-1 receptor agonist Active ingredient Tirzepatide (same as Zepbound/Mounjaro) FDA status Not FDA-approved (compounded) 2026 legality Narrow 503A patient-specific only Typical cost ~$125$449/mo, self-pay Looking for a prescription provider route
Future studies should incorporate standardized performance metrics and direct benchmarking against established fluorescent or MRI contrast agents
The findings also raise concerns about muscle loss, as regular physical activity plays a critical role in preserving lean muscle mass during weight loss