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A temporary hold of one to two weeks during severe GI side effects is a clinically reasonable strategy and does not negate the drug's long-term effectiveness at the maintenance dose

Rather than incentivizing new medicines, patents now primarily drive the adoption of a profit-focused approach

However, research in young, cognitively healthy adults shows limited or no cognitive enhancement, suggesting benefits are most pronounced in individuals with age-related decline, metabolic stress, or neurodegenerative pathology

Posterior parietooccipital hypometabolism may differentiate mild cognitive impairment from dementia in Parkinsons disease

However, no major adverse effects have been reported till now

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