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This may likely be due to the ability of DMSO to prevent the motor control areas in the brain from free radical damage and loss of locomotor function

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J Alzheimers Disease: JAD 86(1):259270

Gutzwiller JP, Tschopp S, Bock A, Zehnder CE, Huber AR, Kreyenbuehl M, Gutmann H, Drewe J, Henzen C, Goeke B, Beglinger C: Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men

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Continuing into the duodenum, pancreatic proteases act on the Hc- Cbl complex