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Yang SH, Xu RX, Cui CJ, Wang Y, Du Y, Chen ZG, et al

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Glucagon Receptor Activation Glucagon increases: Energy expenditure Lipolysis (fat breakdown) Hepatic glucose output Thermogenesis In isolation, glucagon could raise blood sugar levels

Clinical trials and observational studies have demonstrated that nutritional interventions focusing on this pathwayparticularly using methylcobalamin and folinic acidmay lead to measurable improvements in behaviour, communication, and cognitive function for some children with autism, especially those with evidence of methylation pathway dysfunction