doi: 10.1016/j.clinthera.2017.01.005 248
A further disadvantage of ingesting L-Arginine directly is that it is metabolized in the liver by arginase in men with heart disease, arginase is upregulated or more active meaning that more Arginine is converted to the amino acid ornithine, which can potentially lead to herpes outbreaks and other issues
Transcriptome-wide analysis of PGC-1binding RNAs identifies genes linked to glucagon metabolic action
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