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**Study #1-0602, 2024.

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Key Steps Before Starting Semaglutide with Hypothyroidism Before beginning semaglutide, ensure your TSH is stable (typically 0.52.5 mIU/L for most patients) and your levothyroxine dose has not changed for at least 68 weeks

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However, unlike the manufacturer versions, compounded medications are not inspected by the FDA for quality, safety or effectiveness

doi: 10.3389/fpsyt.2025.1589663 Received 10 March 2025 Accepted 06 May 2025 Published 29 May 2025 Volume 16 - 2025 Edited by Paulo Santos, University of Porto, Portugal Reviewed by Martn Garca Juarez, Autonomous University of Nuevo Len, Mexico Gayane Vardanyan, Yerevan State Medical University, Armenia Updates Copyright 2025 Luan, Wang, Shi, Zhang, Wang, Zhou, Wu, Liu, Li, Zhang, Shao, Chen, Chu and Wei