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Tissue hypoxia as micro-hemodynamic status was represented by lactate levels, the macro-hemodynamic status was represented by vasoactive inotropic score (VIS) and mean arterial pressure (MAP), while organ dysfunction severity was represented by the shock index (SI), the sequential organ failure assessment (SOFA) score, and the acute physiology and chronic health evaluation (APACHE) II score
Vitamin B12 deficiency associated with metformin and proton pump inhibitors and their combinations
When combined with vitamin K2, the two work synergistically to support calcium absorption and utilisation
Cui et al., 2023)
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All other reagents employed in this work were analytical grade and were used without further purification
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