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Its HDAC inhibitory activity directly contributes to the reactivation of silenced tumor suppressor genes and is a key mechanism underlying its remarkable anti-tumor effects in urologic and other cancers, as observed both in vitro and in vivo without significant toxicity ( 4.2 Ferroptosis induction: an emerging cell death mechanism Beyond its established roles in apoptosis and cell cycle arrest, SFN demonstrates significant capacity to induce ferroptosisan iron-dependent form of regulated cell death characterized by lethal lipid peroxide accumulation

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adapted the original dermatological mesotherapy technique to develop oral mesotherapy, a procedure that involves the use of fine needles to inject depigmenting agents into the superficial layers of the oral mucosa

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