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Without L-Carnitine, fat struggles to be burned as fuel, leaving your body to tap into muscle protein and glycogen, resulting in reduced muscle strength and stubborn fat reserves that wont budge

The current KDIGO guidelines do not recommend SGLT2i for people in more advanced stages of CKD (eGFR 300 mg/g) and reduced progression of UACR in people with macroalbuminuria when compared with placebo

I typically use the lower end for general metabolic support and higher doses when addressing specific issues like peripheral neuropathy

It is a triple-receptor agonist that simultaneously targets GLP-1, GIP and glucagon receptors

Thats where the other half of the equation comes in

GLP-1s are used as one element within a broader lifestyle change plan rather than the main focus