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(9) and Page et al

Blood Pressure Reductions Participants on the 12mg dose experienced a 14.0 mmHg reduction in systolic blood pressure a clinically meaningful decrease that could translate to reduced cardiovascular events

Specifically, we found no impact of anticoagulant (F 1,11 = 0.2288

Risk is highest during the initial titration phase and subsequent dose increases, particularly in vulnerable populations such as older adults or those with pre-existing conditions

MOTS-c primarily works through metabolic pathways rather than direct hormonal manipulation