semaglutide doesn't work for me Why Stopped Working: 5 Real Reasons & Fixes Your GLP-1 Stopped Working? What

We are surgeons

Even though I could not possibly eat a desert after consuming my mealbecause I was so full, the deserts still sounded good to me

But cost, tolerability, side-effect profiles, and individual response all factor in

This often happens out of habit

Suboptimal dosing : Patients may be on a dose intended for diabetes management (0.5-1.0 mg weekly) rather than the higher dose approved for weight loss (2.4 mg weekly)

Metabolic adaptation : The body naturally adapts to weight loss by reducing metabolic rate, a phenomenon sometimes called "adaptive thermogenesis." This biological response is expected and can slow or plateau weight loss even when medication and lifestyle factors remain consistent