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By adding change in body weight after 5 weeks of treatment as a covariate to the statistical model in a post hoc analysis, the treatment-related differences in 24-h EE as described above were reduced (2%, P =0.21 and 3%, P =0.02 for liraglutide 1.8 mg and 3.0 mg versus placebo, respectively

Lifestyle factors including diet composition, meal timing, sleep quality, and stress levels interact with semaglutide's pharmacological effects

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Rather than promising unproven benefits, focus on patient goals and safe, evidencebased care

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