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The use of electro-acupuncture to stimulate the Zusanli (ST36) acupoint can activate the 7 nicotinic acetylcholine receptor in the lung tissue through the cervical vagus nerve and sciatic nerve to protect the ferroptosis in the lung tissue, which also verifies the importance of the vagus nerve in protecting the oxidative damage of cells (104) ( Figure 2 )

Another interesting observation is that MMP levels increased while TIMP expression decreased, facilitating ECM destruction

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doi: 10.1016/j.biopha.2007.10.011

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