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Historically, the American Society of Anesthesiologists (ASA) had suggested holding GLP-1 receptor agonists prior to elective procedures requiring anesthesia

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Most side effects peak during dose increases and improve as your body adjusts

For brand-name pens, Eli Lilly states that once stored at room temperature, the pen should not be returned to the refrigerator

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The specific threshold for seeking care should be individualized based on clinical judgment and patient factors