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Patients with GHD can present as either childhood-onset (CO-GHD) or adult-onset (AO-GHD)

They are different molecules targeting partially overlapping but distinct receptor pathways

Interestingly, overexpression of the c-KIT tyrosine kinase, a key regulator of melanocytes, has been described in a great number of mucosal melanoma cases (from 39 to 88% depending on the study) and could be a marker or even a target for KIT inhibitors for the treatment of metastatic mucosal melanomas [3, 31]

Arrhythmias due to triggered activity are rare

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Tell your health care provider right away if you have nausea, vomiting, or diarrhea that does not go away severe stomach problems