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GLP-1 medications are not recommended in pregnancy or during breastfeeding

The Medicare GLP-1 Bridge seeks to test whether providing access to GLP-1 products at a uniform, CMS-negotiated net price will help improve beneficiary outcomes and reduce long-term Medicare spending, Kelly Strachan, CMS health insurance specialist and Innovation Center fellow, said, according to The Hill

They work through a coordinated set of effects involving the gut, brain, pancreas, and metabolic system

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Adoption remained modest until recent years as GLP-1 drug claims rose from 6.9 percent in 2023 to 10.5 percent in 2025

Beyond these regions, relevant GLP-1 receptor populations have been identified in at least 10 additional brain areas, pointing to physiological roles that extend well beyond feeding