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Reiss AB et al
Studies show berberine activates the G protein-coupled receptor TGR5, which stimulates L-cells to release GLP-1
Primarily, they act on the hypothalamus to enhance satiety, delay gastric emptying, and reduce caloric intake, leading to a preferential reduction in fat body mass (FBM)
Bu T, Sun Z, Pan Y et al (2024) Glucagon-like peptide-1: new regulator in lipid metabolism
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