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Of the 216 enrolled patients, 102 (47.2%) were not included in the primary analysis because of incomplete questionnaires or loss to follow-up

The dose escalation design tested different starting doses (2 mg vs 4 mg) to evaluate tolerability

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Chemical and physical degradation processes continue at refrigerator temperatures, just at a slower rate

Consistency during dose escalation is actually more important than at any other phase, because your body is adjusting to increasing medication levels and needs stability in all other variables

However, clinical success hinges on the deep integration of interdisciplinary technological innovation within the framework of precision medicine