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[Abstract]2026 Feb;74(2):e70118

Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam

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DCA can activate HIF-2 signaling, increase DMT1 expression, elevate epithelial Fe + accumulation, and trigger ferroptosis

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