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It is not growth hormone itself

52,53 In a phase 2, multi-center trial conducted at 45 centers, orforglipron at doses of 12 mg or greater showed significant reductions in HbA1c and bodyweight compared with placebo or dulaglutide

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Nrf2-dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin-induced cardiotoxicity

Serious adverse events were reported by 4.2% of participants on survodutide, compared to 6.5% of those on placebo