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When two or more IgE molecules are cross-linked by the allergen, the mast cell degranulates

Further evidence indicates that LPS produced in the intestines of SARA cows can translocate into the bloodstream, impair hepatic function, and subsequently accumulate in the mammary gland through the gutlivermammary axis, triggering TLR4NF-BNLRP3-mediated inflammatory responses 178

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Additional testing includes stability assessment under defined storage and handling conditions