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Retatrutide's tri-agonism combines this glucagon arm with both incretin receptors.

The starting dose and maintenance doses of Zepbound (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg) are higher compared to Ozempic (0.5 mg, 1 mg, 2 mg)

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