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Combine resistance training and mobility work to reinforce musculoskeletal adaptations

Preventive treatment may include allopurinol or thiazide diuretics

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INDIRECT PATHWAYS AND EMERGING CONCEPTS Emerging concepts include the influence of the gut microbiota on patient responsiveness to SGLT-2is and GLP-1RAs, which may potentially allow patient selection based on gut microbiota patterns, targeting the microbiota to optimize patterns associated with therapeutic responsiveness and, in essence, a path toward precision and personalized medicine

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Short glossary of useful terms Pharmacodynamic - how a drug affects the body at receptors or tissues