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Nicotine is particularly harmful to developing brains, making it especially dangerous for teenagers and children

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The 2014 FDAs The Real Cost campaign was designed to prevent cigarette initiation, as well as to discourage escalation to persistent smoking, among 1217-year-olds 25

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The primary outcomes of the trial are 5 key harm-reduction metrics: Change in cigarettes smoked per day, The percentage that complete lung cancer screening, Improvements in systolic blood pressure, Improvements in total cholesterol, and Improvements in an overall score of cardiovascular disease risk