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Over time, the vessels no longer hold up to the pressure and rupture

32 Nicotine also affects the vasculature by inducing vasoconstriction, resulting in elevated blood pressure and impaired wound healing in the microvasculature, which is mediated primarily through activation of the homomeric 7 nicotinic acetylcholine receptor expressed on endothelial cells and 1 receptors on vascular smooth muscle cells

Risks related to heart disease, lung conditions, and cancers increase with every additional cigarette smoked, creating a bit of a daily consumption rollercoaster, with a lot fewer thrills and a lot more consequences

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Some companies also offer support programs for employees who want to quit smoking