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However, it should be cautious to interpret causal associations of smoking initiation with suicide attempts, schizophrenia, bipolar disorder and anxiety due to the limitation of instrumental variables used

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[53] tested the rate of pulmonary vascular endothelial cell apoptosis in lung tissue of eleven patients with COPD and ten patients with non-COPD squamous cell lung cancer, measured the expression of mitochondrial transcription factor (mtTFA) mRNA and protein and methylation of the mtTFA promoter

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