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We think it must be doing this by pumping the carcinogenic compounds from cigarette smoke out of the cells allowing them to survive in the toxic environment. Cell surface pumps, including ABCG2, have also been implicated in the development of multidrug resistance in cancers, presumably by pumping the damaging chemotherapy drugs out of cancer cells

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This includes cigarettes, cigars, smokeless tobacco and e-cigarettes

Washington State Expands Tobacco Tax to All Nicotine Products (2026) Senate Bill 5814 refers to a new Washington state law that extends the existing tobacco products tax to encompass all products containing nicotine , regardless of whether the nicotine is derived from tobacco or created synthetically

A randomized trial of E-Cigarettes versus Nicotine-Replacement therapy